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Targeting, Attacking, Eradicating Cancer

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Targeting, Attacking, Eradicating Cancer

Welcome to SillaJen.

Our mission is to be the global leader in oncolytic immunotherapeutics, providing effective therapy to cancer patients and addressing unmet medical needs. We are focused on engineering and developing best-in-class oncolytic virus immunotherapeutics by utilizing our proprietary SOLVE platform which began in a collaboration with Jennerex in 2006.

SillaJen’s lead candidate Pexa-Vec (JX-594) is the first generation oncolytic vaccinia virus from our proprietary SOLVE platform. Over 300 patients have been treated in Pexa-Vec in 13 clinical studies in multiple cancer indications.Pexa-Vec is currently in a multinational Phase 3 clinical trial (PHOCUS in patients with advanced liver cancer, also known as hepatocellular carcinoma (HCC). In US, PHOCUS study is conducted under a special protocol assessment (SPA) granted by the US FDA.

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In addition, our oncolytic immunotherapeutics have shown synergy with chemotherapeutics and immune-oncology therapeutics to for greater efficacy with reduced toxicity.We are now exploring combination strategies to complement immunotherapeutics to bring better therapeutic options to cancer patients.

Thank you for your interest and support of SillaJen.


  • Eun-Sang Moon, M.D., D.D.S
  • Chief Executive Officer