JX-970 is a GM-CSF expressing vaccinia derived from the Western Reserve strain. JX-970 demonstrated tumor debulking efficacy in preclinical studies with enhanced tumor preference and safety.1
• JX-900 is a series of modified vaccinia vaccine (Western Reserve strain) with enhanced oncolytic potency
• Attenuation via “Double-Deletion” : TK (thymidine kinase) & VGF (vaccinia growth factor) gene inactivation.