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JX-900 Series Targeting, Attacking, and Eradicating Cancers®


JX-900 Series Western Reserve Backbone Pipeline




JX-970 is also derived from a Western Reserve strain vaccinia virus. In addition, it expresses GM-CSF to stimulate immune reponses. in preclinical studies, the JX-970 backbone exerted a tumor debulking effect and at the same time demonstrated a selective preference for tumor tissues.1

JX-900 (VVDD)

JX900 (VVDD)

• JX-900 is a series of modified vaccinia vaccine (Western Reserve strain) with enhanced oncolytic potency
• Attenuation via “Double-Deletion” : TK (thymidine kinase) & VGF (vaccinia growth factor) gene inactivation.

Key References: